ZXBio®
ZXBio®
  • HOME
  • ABOUT US
  • International Business
  • Partnerships
  • News
  • 中文版
  • Corporate Official Web
  • Baidu Wiki
  • 更多
    • HOME
    • ABOUT US
    • International Business
    • Partnerships
    • News
    • 中文版
    • Corporate Official Web
    • Baidu Wiki
  • HOME
  • ABOUT US
  • International Business
  • Partnerships
  • News
  • 中文版
  • Corporate Official Web
  • Baidu Wiki

CD11b Monoclonal Antibody (M1/70)

PE Anti-Mouse/Human CD11b (Clone: M1/70) Serum-Free Monoclonal Antibody

Catalog:  ZX022PE-025;ZX022PE-100 

Specifications: 25ug (100ul, 0.25mg/ml) - 100 TEST (100 µl staining volume)

                             100ug (400ul, 0.25mg/ml) - 400 TEST  (100 µl staining volume)

Price: contact us for price information

Product Name: PE Anti-Mouse/Human CD11b (M1/70) Monoclonal Antibody

Description:  CD11b is integrin ITGAM. Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens (PubMed:9558116, PubMed:20008295). It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin ITGAM/ITGB2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. Regulates neutrophil migration (PubMed:28807980). In association with beta subunit ITGB2/CD18, required for CD177-PRTN3-mediated activation of TNF primed neutrophils (PubMed:21193407). May regulate phagocytosis-induced apoptosis in extravasated neutrophils (By similarity). May play a role in mast cell development (By similarity). Required with TYROBP/DAP12 in microglia to control production of microglial superoxide ions which promote the neuronal apoptosis that occurs during brain development (By similarity). [provided by UniProtKB]   

Specificity:Against Mouse/Human CD11b Antigen

Host:Rat

Application:Flow Cytometry (For Research Purpose Only)

Each lot of this antibody is quality control tested with flow cytometric analysis. The amount of the reagent is suggested to be used ≤ 0.125 µg /10^6 cells in 100 µl. Typically we suggest to use 1:100 titration for staining 1 millions cells in 100 µl staining. Since applications vary, the appropriate dilutions must be determined for individual use.

Figure (Flow Cytometric Analysis): 1 million mouse splenocytes were stained with 0.125µg CD11b-PE.

Product Manual

ZX022PE 抗鼠CD11b(Mac-1)流式单抗(PE)[M1 70] (pdf)下载

National State Enterprise Credit Information 

  • 企业工商信息

Copyright © 2023 ZXBio® - All Rights Reserved.